Cell and Protein Expression Core


Paresh Sanghani, Ph.D.
1345 West Sixteenth Street, L3 321
(317) 278-8465
(317) 278-9739 FAX

The Cell and Protein Expression Core laboratory is a service laboratory whose primary goal is to assist investigators at Indiana University in protein structure-function studies. Core personnel provide assistance in the selection of an optimal recombinant expression system (prokaryotic and eukaryotic), subcloning genes of interest into expression vectors, and in optimizing protein expression and purification. The core also assists in the generation of site-directed mutants of the proteins of interest and in scaling up of recombinant protein production.